Terahertz-Based Porosity Measurement of Pharmaceutical Tablets: a Tutorial
نویسندگان
چکیده
منابع مشابه
Hardness and density distributions of pharmaceutical tablets measured by terahertz pulsed imaging.
We present terahertz pulsed imaging (TPI) as a novel tool to quantify the hardness and surface density distribution of pharmaceutical tablets. Good agreement between the surface refractive index (SRI) measured by TPI and the crushing force measured from diametral compression tests was found using a set of tablets that were compacted at various compression forces. We also found a strong correlat...
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There has been a significant and growing interest in chemical imaging of pharmaceutical tablets in recent years. Technology improvements and increased use has established chemical imaging as a means of providing information on certain critical quality parameters that is not readily addressable using other techniques. In addition to major pharmaceutical manufacturers, generic manufacturers and e...
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TERAHERTZ LIGHT Terahertz (THz=10Hz) radiation represents the last unexplored frontier of the radio wave and light spectrum. The so-called ‘Terahertz Gap’ encompasses frequencies invisible to the naked eye in the range from 100GHz (10Hz) up to roughly 30THz (3x10Hz). The former limit lies just above the microwave region, whereas the latter limit is located adjacent to infrared frequencies; the ...
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Individual layer weight control is a critical issue for bilayer tablets during manufacturing process. Despite its importance for ensuring product content uniformity, few studies have investigated the possibility of developing a process analytical technology (PAT) tool to monitor the individual layer control. We introduced the use of Terahertz time-domain measurement because of its fast measurem...
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ژورنال
عنوان ژورنال: Journal of Infrared, Millimeter, and Terahertz Waves
سال: 2020
ISSN: 1866-6892,1866-6906
DOI: 10.1007/s10762-019-00659-0